SCHEMBL8699754

SCHEMBL8699754

CC(=O)N(CCC1CCNCC1)S(=O)(=O)c1ccc(C)cc1N1CCN(c2ccncc2)CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.36
ACHE P22303 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
RORC P51449 1/20 0.34
ADRB2 P07550 1/20 0.33
NCF1 P14598 1/20 0.33
PLD1 Q13393 1/20 0.33
F10 P00742 4/20 0.33
CHRM1 P11229 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.32
BDKRB1 P46663 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.32
ITGB3 P05106 1/20 0.32
ITGA2B P08514 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8701209 0.91 L3MBTL1 (0.37) L3MBTL1CA12CA1CA2CA9
SCHEMBL8632400 0.80 MEN1 (0.39) CA12CA1CA2CA9RORC
SCHEMBL8634739 0.74 CA12 (0.41) CA12CA1CA2CA9KMT2A
SCHEMBL8633897 0.67 HRH3 (0.35) ADRB2NCF1PLD1F10CHRM1
Hydrochloric Acid SCHEMBL8838142 0.65 ADRB2 (0.41) ADRB2NCF1PLD1BDKRB1ITGB3
SCHEMBL8637013 0.65 ITGB3 (0.38) RORCADRB2NCF1PLD1F10
SCHEMBL8634130 0.65 ITGB3 (0.39) RORCADRB2NCF1PLD1F10
SCHEMBL14624181 0.64 DRD2 (0.60) ADRB2NCF1PLD1
Hydrochloric Acid SCHEMBL8838050 0.64 ADRB2 (0.38) ADRB2NCF1PLD1BDKRB1ITGB3
SCHEMBL6152361 0.64 CHRM4 (0.51) ADRB2NCF1PLD1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750754-A TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS ZENECA LIMITED (GB) 1998-05-12 US disclosed