Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.48 |
| ▸ | CES1 | P23141 | 9/20 | 0.44 |
| ▸ | CES2 | O00748 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11881585 | 0.82 | AKR1B1 (0.50) | FAAHCES1CES2AKR1B1 | |
| SCHEMBL4510325 | 0.80 | GPR84 (0.52) | FAAHCES1CES2AKR1B1 | |
| SCHEMBL4794021 | 0.80 | CA2 (0.45) | FAAHCES1CES2CA2ENPP2 | |
| SCHEMBL10917863 | 0.79 | FAAH (0.54) | FAAHCES1CES2CA2ENPP2 | |
| SCHEMBL5015091 | 0.78 | CA2 (0.48) | FAAHCES1CES2CA2 | |
| SCHEMBL10616097 | 0.77 | ENPP2 (0.47) | FAAHCES1CES2CA2ENPP2 | |
| SCHEMBL4554474 | 0.75 | ENPP2 (0.46) | FAAHCES1CES2CA2ENPP2 | |
| SCHEMBL5313008 | 0.73 | CA2 (0.43) | FAAHCES1CES2CA2ENPP2 | |
| SCHEMBL11336 | 0.72 | — | — | |
| Bicarbonate SCHEMBL28303753 | 0.72 | EPHX2 (0.53) | FAAHCES1CES2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000408-A1 | N-PHENYLIMINO HETEROCYCLIC DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1998-01-08 | — | — | WO | disclosed |