Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699803 | 0.91 | GAA (0.56) | GAALMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8635011 | 0.77 | ITGB3 (0.48) | GAASMN1; SMN2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8837973 | 0.76 | ITGB3 (0.47) | GAAALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL27908881 | 0.76 | DRD2 (0.72) | HSD17B10DRD2 | |
| SCHEMBL8637900 | 0.75 | OPRD1 (0.42) | LMNASMN1; SMN2ALDH1A1TSHRF2 | |
| SCHEMBL7947475 | 0.75 | KMT2A (0.52) | SMN1; SMN2ALDH1A1KMT2ADRD2HTR1A | |
| SCHEMBL2355678 | 0.75 | DRD3 (0.72) | DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL8635826 | 0.74 | HRH3 (0.54) | GAASMN1; SMN2ALDH1A1TSHRDRD2 | |
| Hydrochloric Acid SCHEMBL8837964 | 0.74 | ITGB3 (0.45) | TSHR | |
| SCHEMBL8630600 | 0.73 | HRH3 (0.55) | GAASMN1; SMN2ALDH1A1TSHRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |