Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 8/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634318 | 0.87 | PDE4B (0.46) | TBXA2RMCL1ALDH1A1 | |
| SCHEMBL8635360 | 0.86 | TBXA2R (0.41) | TBXA2RMCL1MERTKALDH1A1 | |
| SCHEMBL8631102 | 0.85 | AKR1C3 (0.47) | ALDH1A1 | |
| SCHEMBL8633408 | 0.84 | ALDH1A1 (0.39) | TBXA2RALDH1A1 | |
| SCHEMBL8635463 | 0.84 | AKR1C3 (0.45) | BRD4ALDH1A1 | |
| SCHEMBL7761272 | 0.83 | SLC9A1 (0.57) | — | |
| SCHEMBL27348370 | 0.83 | VNN1 (0.43) | — | |
| SCHEMBL8634936 | 0.82 | AKR1C3 (0.48) | ALDH1A1 | |
| SCHEMBL8635344 | 0.81 | KMT2A (0.36) | ALDH1A1 | |
| SCHEMBL27526953 | 0.81 | RAPGEF4 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |