Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630374 | 1.00 | USP2 (0.34) | USP2EGFRALDH1A1KDM4ELMNA | |
| SCHEMBL8635781 | 0.87 | TLR2 (0.35) | EGFRALDH1A1KDM4ELMNAKDM1A | |
| Hydrochloric Acid SCHEMBL8629084 | 0.80 | CFD (0.38) | EGFRALDH1A1KDM4EKDM1APOLB | |
| SCHEMBL8632827 | 0.77 | RIPK1 (0.36) | ALDH1A1KDM4EKDM1AKMT2AMAPT | |
| SCHEMBL9016430 | 0.76 | USP2 (0.47) | USP2EGFRALDH1A1KDM4ELMNA | |
| SCHEMBL8630378 | 0.75 | SRC (0.34) | USP2 | |
| SCHEMBL7392981 | 0.65 | KCNA5 (0.41) | POLB | |
| SCHEMBL5026445 | 0.65 | KDM4E (0.42) | EGFRALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL31455672 | 0.63 | KDM4E (0.40) | EGFRALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL4893812 | 0.63 | ALDH1A1 (0.44) | EGFRALDH1A1KDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |