Styrene

Styrene

SCHEMBL8635873

C=Cc1ccccc1.CCCCC(=CC=C(C)C(=O)O)C(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.42
ALOX5 P09917 4/20 0.42
PTGES O14684 3/20 0.42
PPARG P37231 2/20 0.42
LMNA P02545 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
APEX1 P27695 1/20 0.36
ELANE P08246 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
EGFR P00533 1/20 0.35
HDAC3 O15379 1/20 0.35
RECQL P46063 1/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7110641 0.89 ALOX5 (0.43) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL10808703 0.87 AKR1C3 (0.46) AKR1C3TDP1ALDH1A1TSHRCYP3A4
Styrene SCHEMBL9725237 0.85 LMNA (0.45) ALOX5PTGESPPARGLMNATDP1
SCHEMBL2940335 0.83 CES1 (0.40) PPARGTDP1ALDH1A1TSHRCES2
Styrene SCHEMBL27585078 0.83 ALOX5 (0.43) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL2042273 0.81 AKR1C3 (0.42) AKR1C3ALOX5PTGESPPARGLMNA
Styrene SCHEMBL258132 0.79 LMNA (0.47) AKR1C3ALOX5PTGESPPARGLMNA
Styrene SCHEMBL17065130 0.79 LMNA (0.47) AKR1C3ALOX5PTGESPPARGLMNA
Styrene SCHEMBL5270544 0.79 LMNA (0.47) AKR1C3ALOX5PTGESPPARGLMNA
SCHEMBL8437309 0.79 CYP2C19 (0.36) AKR1C3ALOX5PTGESPPARGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723113-A NONIONIC AND CATIONIC ACRYLIC POLYMERS CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-03-03 US disclosed
US-5599532-A BLEND OF NONIONIC POLYMER AND ANIONIC POLYMER CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1997-02-04 US disclosed