Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31327793 | 1.00 | ACHE (0.50) | ACHECES2CES1CA1CA2 | |
| SCHEMBL2153528 | 0.94 | CA4 (0.48) | ACHECES2CES1CA1CA2 | |
| SCHEMBL28433395 | 0.83 | ACHE (0.47) | ACHECES2CES1CA1CA2 | |
| SCHEMBL13081390 | 0.83 | CES2 (0.50) | ACHECES2CES1CA1CA2 | |
| SCHEMBL2859493 | 0.79 | ALDH1A1 (0.61) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL2155175 | 0.78 | KIF11 (0.38) | ALDH1A1CYP3A4LMNAMEN1POLB | |
| SCHEMBL2155513 | 0.78 | TP53 (0.53) | ALDH1A1CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL2154958 | 0.78 | RXRA (0.46) | CA2ALDH1A1PRSS1LMNAMEN1 | |
| SCHEMBL13970485 | 0.77 | ALDH1A1 (0.43) | ACHECES2CES1CA1CA2 | |
| SCHEMBL8637786 | 0.76 | NFE2L2 (0.49) | ALDH1A1LMNAMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669070-B | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2021-08-27 | — | — | CN | claimed |
| CN-110669070-A | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2020-01-10 | — | — | CN | claimed |
| CN-120004942-A | Method for synthesizing phosphorothioate compound by using manganese acetate dihydrate | 苏州大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-118996447-A | Phosphine-oxide substituted quinoxaline quinazolinone compound, preparation method and application thereof | 南阳师范学院 | 2024-11-22 | — | — | CN | disclosed |
| CN-115403623-B | Method for preparing 2-pyrrolyl substituted phosphine oxide compound | 湖南理工学院 | 2024-10-29 | — | — | CN | disclosed |
| CN-116836198-A | Synthesis method of 2-aryl-4-phosphono-4H-chromene compound | 成都大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-116462706-A | Synthesis method of organic phosphonyl fluoride compound | 湖南科技大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-116237068-A | Preparation method of 2-phosphonomethyl phenol compound | 广西中烟工业有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-115322222-A | Photocatalytic preparation method of ((alkylamino) methyl) diphenyl phosphine oxide compound | 河南师范大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-110669070-B | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-110669070-A | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2020-01-10 | — | — | CN | disclosed |
| US-9120826-B1 | Olefin hydroboration | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2015-09-01 | — | — | US | disclosed |
| WO-2015094207-A1 | PHOSPHINYL FORMAMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2015-06-25 | — | — | WO | disclosed |
| US-8865610-B2 | Phosphinyl guanidine compounds, metal salt complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-10-21 | — | — | US | disclosed |
| US-20140221645-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-08-07 | — | — | US | disclosed |
| US-8680003-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-03-25 | — | — | US | disclosed |
| US-20130331629-A1 | Phosphinyl Guanidine Compounds, Metal Salt Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-12-12 | — | — | US | disclosed |
| US-20120309965-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-12-06 | — | — | US | disclosed |
| EP-2519532-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | Chevron Phillips Chemical Company LP (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082192-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309965-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | NIT2, NCLN, NPM1 | ACHE 1107/4885CES2 4230/4885CES1 4516/4885 |
| US-20140221645-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | NIT2, NCLN, NPM1 | ACHE 1107/4885CES2 4230/4885CES1 4516/4885 |
| US-20130331629-A1 | Phosphinyl Guanidine Compounds, Metal Salt Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | GMPS, ITPA, GEMIN4 | ACHE 1474/4885CES2 4072/4885CES1 4729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.