Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.37 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8355556 | 0.86 | KMT2A (0.47) | KMT2AMEN1ALDH1A1CHRM1TET3 | |
| SCHEMBL8302463 | 0.83 | ITGA4 (0.46) | KMT2AMEN1ALDH1A1LMNAITGA4 | |
| Hydrochloric Acid SCHEMBL8350428 | 0.82 | ITGA4 (0.45) | KMT2AMEN1ALDH1A1LMNAITGA4 | |
| SCHEMBL27953257 | 0.81 | ITGA4 (0.48) | KMT2AMEN1ALDH1A1LMNACHRM1 | |
| SCHEMBL7467936 | 0.77 | OPRM1 (0.45) | KMT2AMEN1ALDH1A1LMNAITGA4 | |
| SCHEMBL18390235 | 0.76 | HSD11B1 (0.53) | KMT2AMEN1ALDH1A1LMNACHRM1 | |
| SCHEMBL8638673 | 0.76 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1LMNAITGA4 | |
| Hydrochloric Acid SCHEMBL8347400 | 0.76 | OPRM1 (0.44) | KMT2AMEN1ALDH1A1LMNAITGA4 | |
| Hydrochloric Acid SCHEMBL8355525 | 0.75 | HSD11B1 (0.52) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8349941 | 0.74 | HSD11B1 (0.54) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |