Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 13/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639290 | 0.83 | CHRM3 (0.41) | FKBP1ACHRM3ALOX5HDAC6 | |
| SCHEMBL8639279 | 0.80 | HTR1E (0.39) | F2EPHX2ALOX5HDAC6 | |
| SCHEMBL8639284 | 0.77 | F2 (0.41) | FKBP1AF2EPHX2 | |
| SCHEMBL8637023 | 0.77 | ALOX5 (0.40) | CHRM3EPHX2ALOX5HDAC6 | |
| SCHEMBL28194907 | 0.75 | ALDH1A1 (0.53) | FKBP1AF2 | |
| SCHEMBL8636307 | 0.72 | CHRM3 (0.49) | CHRM3EPHX2ALOX5HDAC6 | |
| SCHEMBL8634916 | 0.69 | CHRM3 (0.47) | CHRM3ALOX5HDAC6 | |
| SCHEMBL1177706 | 0.69 | HTR1E (0.60) | CHRM3ALOX5HDAC6 | |
| SCHEMBL1177709 | 0.69 | HTR1E (0.60) | CHRM3ALOX5HDAC6 | |
| SCHEMBL4682506 | 0.68 | KMT2A (0.44) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521206-A | HYPOTENSIVE AGENTS, TREATMENT OF ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |