SCHEMBL8640682

SCHEMBL8640682

CC(C)(C)Oc1c(-c2ccccc2)c(=O)c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
PDE4B Q07343 4/20 0.36
PDE4A P27815 3/20 0.36
PDE4C Q08493 3/20 0.36
PDE4D Q08499 3/20 0.36
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 4/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP3A4 P08684 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RCE1 Q9Y256 1/20 0.33
PDGFRA P16234 1/20 0.33
MAPK8 P45983 1/20 0.33
CDK5 Q00535 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9760097 0.78 PDE4B (0.53) LMNAMAPTHTTPDE4BPDE4A
SCHEMBL9509519 0.74 MAPT (0.48) LMNAMAPTHTTPDE4BPDE4A
SCHEMBL3943393 0.73 MAPT (0.46) LMNAMAPTHTTPDE4BPDE4A
SCHEMBL18698344 0.73 PDE4B (0.41) LMNAMAPTHTTPDE4BPDE4A
SCHEMBL9760352 0.73 LMNA (0.46) LMNAMAPTHTTPDE4BPDE4A
SCHEMBL6324941 0.71 PDE4B (0.55) LMNAMAPTHTTPDE4BPDE4A
SCHEMBL18392174 0.71 HTT (0.88) LMNAMAPTHTTKMT2AMEN1
SCHEMBL14125006 0.69 PDCD1 (0.38) ALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL9554998 0.69 LTA4H (0.49) LMNAMAPTHTTALDH1A1L3MBTL1
SCHEMBL17036082 0.68 PDE4B (0.37) MAPTPDE4BPDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665789-B1 HEAT-SENSITIVE IMAGE RECORDING MEDIUM AND PROCESS POLAROID CORP (US) 1997-01-22 EP claimed
EP-0665789-A1 HEAT-SENSITIVE IMAGE RECORDING MEDIUM AND PROCESS. POLAROID CORP (US) 1995-08-09 EP claimed
WO-1994009992-A1 HEAT-SENSITIVE IMAGE RECORDING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 WO claimed
EP-0665960-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1998-08-19 EP disclosed
US-5667943-A SQUARIC ACID DERIVATIVES, LEUCO DYES POLAROID CORPORATION (US) 1997-09-16 US disclosed
EP-0665789-B1 HEAT-SENSITIVE IMAGE RECORDING MEDIUM AND PROCESS POLAROID CORP (US) 1997-01-22 EP disclosed
US-5578424-A EXPOSING A MIXTURE OF AN ACID PRECURSOR AND A DYE TO ACTINIC RADIATION TO DECOMPOSE PRECURSOR POLAROID CORPORATION (US) 1996-11-26 US disclosed
EP-0665961-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1996-10-02 EP disclosed
US-5534388-A SUPERACID PRECURSOR IS EXPOSED TO ACTINIC RADIATION TO GENERATE SUPERACID; COLORIMETRIC ANALYSIS POLAROID CORPORATION (US) 1996-07-09 US disclosed
US-5534393-A SQUARIC ACID DERIVATIVES FOR LEUCO DYES IN IMAGING POLAROID CORPORATION (US) 1996-07-09 US disclosed
US-5453345-A Imaging medium POLAROID CORPORATION (US) 1995-09-26 US disclosed
EP-0665961-A1 IMAGING MEDIUM AND PROCESS. POLAROID CORP (US) 1995-08-09 EP disclosed
US-5401619-A Cyclobut-3-ene-1,2-dione, a dye and a binder POLAROID CORPORATION (US) 1995-03-28 US disclosed
US-5395736-A Exposing superoxide precursor to actinic radiation, generating superacid, mixing with oxalic acid diester, heating POLAROID CORPORATION (US) 1995-03-07 US disclosed
US-5334489-A Hydroxylating 3,4-disubstituted-cyclobut-3-ene-1,2-dione by heating in presence of acid catalysts which is generated by exposing actinic radiation from superacid precursor POLAROID CORPORATION (US) 1994-08-02 US disclosed
WO-1994009992-A1 HEAT-SENSITIVE IMAGE RECORDING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 WO disclosed
WO-1994010606-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 WO disclosed
WO-1994010607-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 WO disclosed
US-5286612-A Mixture of superacid precursor and dye POLAROID CORPORATION (US) 1994-02-15 US disclosed
US-5278031-A Neutralization of acid compounds and reverse coloring POLAROID CORPORATION (US) 1994-01-11 US disclosed