Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760097 | 0.83 | PDE4B (0.53) | MAPTHTTLMNAPDE4BPDE4A | |
| SCHEMBL6324941 | 0.77 | PDE4B (0.55) | MAPTHTTLMNAPDE4BPDE4A | |
| SCHEMBL9760352 | 0.74 | LMNA (0.46) | MAPTHTTLMNAPDE4BPDE4A | |
| SCHEMBL3943393 | 0.74 | MAPT (0.46) | MAPTHTTLMNAPDE4BPDE4A | |
| SCHEMBL8640682 | 0.74 | LMNA (0.46) | MAPTHTTLMNAPDE4BPDE4A | |
| SCHEMBL10437520 | 0.74 | ALDH1A1 (0.46) | MAPTALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18392174 | 0.72 | HTT (0.88) | MAPTHTTLMNAALDH1A1MEN1 | |
| SCHEMBL18677105 | 0.71 | DYRK1A (0.49) | CYP3A4CLK4 | |
| SCHEMBL9554998 | 0.71 | LTA4H (0.49) | MAPTHTTLMNAALDH1A1CYP1A2 | |
| SCHEMBL1760851 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396828-B1 | UNSYMMETRICAL SQUARAINE COMPOSITIONS AND PHOTOCONDUCTIVE IMAGING MEMBERS USING SUCH COMPOSITIONS | XEROX CORPORATION (US) | 1993-08-11 | — | — | EP | disclosed |
| US-5030537-A | Photoconductive unsymmetrical squaraine compositions | XEROX CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0396828-A1 | Unsymmetrical squaraine compositions and photoconductive imaging members using such compositions | XEROX CORPORATION (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4922018-A | Photoconductive imaging members with unsymmetrical squaraine compositions | XEROX CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| US-4886722-A | Photoconductive imaging members with unsymmetrical squaraine compositions | XEROX CORPORATION (US) | 1989-12-12 | — | — | US | disclosed |