Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639234 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TDP1LMNASLC6A2HTR2B | |
| SCHEMBL8642271 | 0.82 | GABRA1 (0.34) | GABRA1GABRB2GABRG2GABRB3FAAH | |
| SCHEMBL8639222 | 0.81 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL8645901 | 0.81 | HTR2A (0.46) | ALDH1A1CYP2D6CYP2C19HSD17B10HTR2A | |
| SCHEMBL8639418 | 0.81 | HTR2C (0.31) | GBA1HTR2C | |
| SCHEMBL8153294 | 0.80 | GABRA1 (0.33) | GABRA1GABRB2GABRG2GABRB3FAAH | |
| SCHEMBL8640118 | 0.78 | SLC22A1 (0.38) | ALDH1A1HTR2AHRH1TDP1CA1 | |
| SCHEMBL8645772 | 0.78 | TRPA1 (0.36) | LMNAPTGS1 | |
| SCHEMBL8642476 | 0.75 | ALDH1A1 (0.34) | ALDH1A1LMNASLC6A2 | |
| SCHEMBL8639375 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TDP1LMNASLC6A2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |