SCHEMBL8647155

SCHEMBL8647155

CC(C)CC1NC(=O)OC1=O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 2/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.33
PAX8 Q06710 1/20 0.33
PRCP P42785 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265958 1.00 MEN1 (0.36) MEN1KMT2AGAALMNACYP3A4
SCHEMBL29390301 1.00 MEN1 (0.36) MEN1KMT2AGAALMNACYP3A4
SCHEMBL12449150 1.00 MEN1 (0.36) MEN1KMT2AGAALMNACYP3A4
SCHEMBL14553368 0.80 MEN1 (0.37) MEN1KMT2AGAALMNACYP3A4
SCHEMBL1643317 0.76
SCHEMBL762450 0.76
SCHEMBL24420094 0.75 HTT (0.33) MEN1KMT2AGAALMNACYP3A4
SCHEMBL4405125 0.73
SCHEMBL7662496 0.72 SMN1; SMN2 (0.34) MEN1KMT2A
SCHEMBL13498357 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024028255-A1 POLY(AMINO ACID) BASED CAPSULES AGFA-GEVAERT NV (BE) 2024-02-08 WO disclosed
WO-2023003515-A2 FUNCTIONALISED POLYPEPTIDES, NANOPARTICLES AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-01-26 WO disclosed
WO-2022194759-A1 POLY(AMINO ACID) BASED CAPSULES AGFA-GEVAERT NV (BE) 2022-09-22 WO disclosed
EP-4019493-A1 METHOD FOR PRODUCING CARBONYL COMPOUND AND FLOW REACTION SYSTEM USED FOR PRODUCTION OF CARBONYL COMPOUND FUJIFILM Corporation (JP) 2022-06-29 EP disclosed
US-20220144760-A1 METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND FUJIFILM CORPORATION (JP) 2022-05-12 US disclosed
US-20220135517-A1 METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND FUJIFILM CORPORATION (JP) 2022-05-05 US disclosed
CN-111643674-B Polyamino acid carrier with middle acid-sensitive connecting arm and preparation method and application thereof 中国药科大学 2022-03-25 CN disclosed
EP-3572408-B1 METHOD FOR PURIFYING AN AMINO ACID-N-CARBOXY ANHYDRIDE SHINETSU CHEMICAL CO (JP) 2021-10-27 EP disclosed
CN-111534494-B (R) -omega-transaminase mutant and application thereof in preparation of sitagliptin intermediate 浙江工业大学 2021-10-01 CN disclosed
CN-111411094-B (R) -omega-transaminase mutant and application thereof 浙江工业大学 2021-10-01 CN disclosed
CN-110951706-A Recombinant R-omega-transaminase, mutant and application in asymmetric synthesis of sitagliptin 浙江工业大学 2020-04-03 CN disclosed
CN-110904066-A Recombinant R-type transaminase, mutant and application thereof 浙江工业大学 2020-03-24 CN disclosed
US-8841440-B2 Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof CORNELL UNIVERSITY (US) 2014-09-23 US disclosed
US-8841440-B2 Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof CORNELL UNIVERSITY (US) 2014-09-23 US disclosed
US-20130143821-A1 HYDROPHOBICALLY-MODIFIED HYALURONAN AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-06-06 US disclosed
US-20110150999-A1 Organo-Soluble Chitosan Salts and Chitosan-Derived Biomaterials Prepared Thereof CORNELL UNIVERSITY 2011-06-23 US disclosed
US-20110150999-A1 Organo-Soluble Chitosan Salts and Chitosan-Derived Biomaterials Prepared Thereof CORNELL UNIVERSITY 2011-06-23 US disclosed
US-5750735-A CHEMICAL INTERMEDIATES FOR ANTIBIOTICS AMERICAN CYANAMID COMPANY (US) 1998-05-12 US disclosed
US-5744465-A Method of inhibiting a β-lactamase enzyme by administering novel 2-thiosubstituted carbapenems AMERICAN CYANAMID COMPANY (US) 1998-04-28 US disclosed
US-5623081-A USING BENZYLOXYACETALDEHYDE DIMETHYL ETHER, HALOGENATED 1-PHENYLMETHOXY-4-PENTEN-2-OL; CYCLIZATION LIN YANG-I (US) 1997-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135517-A1 METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND PARG, PTGIS, MT-ATP8 MEN1 3206/4885KMT2A 3614/4885GAA 3126/4885
US-20130143821-A1 HYDROPHOBICALLY-MODIFIED HYALURONAN AND METHODS OF MAKING AND USING THEREOF CD44, HPSE, HACD3 MEN1 1281/4885KMT2A 3730/4885GAA 682/4885
US-20110150999-A1 Organo-Soluble Chitosan Salts and Chitosan-Derived Biomaterials Prepared Thereof CHIA, CHI3L2, CHI3L1 MEN1 1357/4885KMT2A 4282/4885GAA 1360/4885
US-20220144760-A1 METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND NOXO1, MT-CO2, MT-ATP8 MEN1 3530/4885KMT2A 2633/4885GAA 2284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.