Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Gallic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | SELL | P14151 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SELP | P16109 | 1/20 | 0.54 |
| ▸ | FUT4 | P22083 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gallic Acid SCHEMBL2589994 | 0.97 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL729825 | 0.97 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL28109427 | 0.95 | CA2 (0.54) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL4276877 | 0.95 | KDM4E (0.54) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL4276882 | 0.95 | KDM4E (0.54) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL28212205 | 0.95 | KDM4E (0.54) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL8649680 | 0.95 | KDM4E (0.54) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL28654164 | 0.95 | KDM4E (0.59) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL338355 | 0.92 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL15529595 | 0.92 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688738-B1 | A gallium silicate having 12-ring pores (ECR-34) and a method for its preparation | EXXON RESEARCH ENGINEERING CO (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0688738-A2 | A gallium silicate having 12-ring pores (ECR-34) and a method for its preparation | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1995-12-27 | — | — | EP | disclosed |
| US-5455020-A | Hydrated zeolite containing oxides of potassium, sodium, aluminum, gallium and silicon, and tetraethylammonium ion; hydrorefining catalysts, adsorbers | EXXON RESEARCH & ENGINEERING CO. (US) | 1995-10-03 | — | — | US | disclosed |