Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Gallic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.54 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.54 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.54 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.54 |
| ▸ | XDH known ✓ | P47989 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | SELL | P14151 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SELP | P16109 | 1/20 | 0.54 |
| ▸ | FUT4 | P22083 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gallic Acid SCHEMBL729825 | 0.97 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL28109427 | 0.95 | CA2 (0.54) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL8649681 | 0.95 | KDM4E (0.54) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL28654164 | 0.95 | KDM4E (0.59) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL17748260 | 0.92 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL9185403 | 0.92 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL15529595 | 0.92 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL21273260 | 0.92 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL21273262 | 0.92 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 | |
| Gallic Acid SCHEMBL1738962 | 0.92 | KDM4E (0.56) | KDM4ELMNATDP1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115133159-A | Functional aqueous zinc ion battery electrolyte and preparation method and application thereof | 河南师范大学 | 2022-09-30 | — | — | CN | claimed |
| CN-115133159-A | Functional aqueous zinc ion battery electrolyte and preparation method and application thereof | 河南师范大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-107961239-B | Triple pharmaceutical composition and application thereof in treating gastroenteritis | 陕西君碧莎制药有限公司 | 2020-03-13 | — | — | CN | disclosed |
| CN-107961239-A | A kind of three pharmaceutical composition and its application in terms of enterogastritis is treated | 陕西君碧莎制药有限公司 | 2018-04-27 | — | — | CN | disclosed |