Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650351 | 0.90 | KMT2A (0.52) | KMT2ASMN1; SMN2MEN1HRH3SIGMAR1 | |
| SCHEMBL7286228 | 0.82 | KMT2A (0.45) | KMT2ASMN1; SMN2MEN1HRH3SIGMAR1 | |
| SCHEMBL8648284 | 0.80 | SMN1; SMN2 (0.59) | KMT2ASMN1; SMN2MEN1HRH3HTT | |
| SCHEMBL8643896 | 0.77 | SIGMAR1 (0.44) | KMT2AMEN1HRH3SIGMAR1GRM5 | |
| SCHEMBL8644239 | 0.77 | SLC6A3 (0.48) | HRH3SIGMAR1GRM5GSK3BHRH1 | |
| SCHEMBL3363422 | 0.76 | HRH3 (0.51) | KMT2ASMN1; SMN2HRH3 | |
| SCHEMBL5376326 | 0.74 | CALCRL (0.51) | — | |
| SCHEMBL7378187 | 0.74 | ALDH1A1 (0.58) | GRM5 | |
| SCHEMBL21793705 | 0.74 | GSK3B (0.53) | SIGMAR1GSK3BHTR1ADRD2HTR2A | |
| SCHEMBL14489806 | 0.74 | MCHR1 (0.72) | KMT2ASMN1; SMN2HRH3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |