Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MTTP | P55157 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654366 | 0.92 | KMT2A (0.40) | DRD3DRD2DRD4ADRA2ASLC6A2 | |
| SCHEMBL8648478 | 0.89 | CCNE1 (0.37) | POLBDRD3CNR1MTTPCHRM2 | |
| SCHEMBL8717984 | 0.85 | CCR3 (0.42) | SLC6A12POLBDRD3DRD2NPSR1 | |
| SCHEMBL8712539 | 0.83 | CCR3 (0.42) | SLC6A12POLBDRD3DRD2MTTP | |
| SCHEMBL8665881 | 0.83 | DRD2 (0.37) | POLBDRD3DRD2DRD4NPSR1 | |
| SCHEMBL8713182 | 0.83 | CKS1B (0.38) | POLBDRD3DRD2DRD4CNR1 | |
| SCHEMBL8593680 | 0.82 | POLB (0.42) | POLBDRD3DRD2DRD4NPSR1 | |
| SCHEMBL8665519 | 0.81 | CCR3 (0.40) | DRD2 | |
| SCHEMBL8666097 | 0.81 | DRD2 (0.36) | POLBDRD3DRD2DRD4NPSR1 | |
| SCHEMBL8712881 | 0.80 | POLB (0.35) | POLBDRD3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |