Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651966 | 0.89 | SLC6A12 (0.36) | LMNATP53CNR1CHRM2ADRA2A | |
| SCHEMBL8717984 | 0.87 | CCR3 (0.42) | CCR3MEN1KMT2ACHRM2ADRA2A | |
| SCHEMBL8654366 | 0.86 | KMT2A (0.40) | ALDH1A1LMNASMN1; SMN2TP53MEN1 | |
| SCHEMBL8712539 | 0.85 | CCR3 (0.42) | CCR3MEN1KMT2ACHRM2ADRA2A | |
| SCHEMBL8665881 | 0.83 | DRD2 (0.37) | KMT2ACHRM1DRD3MTTPPOLB | |
| SCHEMBL8665519 | 0.83 | CCR3 (0.40) | CCR3 | |
| SCHEMBL8713182 | 0.83 | CKS1B (0.38) | ALDH1A1CNR1HTR2ADRD3POLB | |
| SCHEMBL8593680 | 0.82 | POLB (0.42) | ALDH1A1LMNATP53KMT2ADRD3 | |
| SCHEMBL8480060 | 0.82 | CCR3 (0.40) | CCNE1CDK2CCR3MEN1KMT2A | |
| SCHEMBL8666097 | 0.81 | DRD2 (0.36) | KMT2ACHRM1DRD3MTTPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |