SCHEMBL865488

SCHEMBL865488

C=C(C)C(=O)OC(C)([O])CC

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.39
TSHR P16473 3/20 0.38
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108024 0.80 TSHR (0.43) ALDH1A1THRBTSHRGAA
SCHEMBL347723 0.80 ALDH1A1 (0.42) ALDH1A1THRBTSHRGAA
SCHEMBL2234565 0.80 ALDH1A1 (0.42) ALDH1A1THRBTSHRGAA
SCHEMBL25561392 0.78 ALDH1A1 (0.41) ALDH1A1THRBTSHRGAA
Ammonia Solution, Strong SCHEMBL1735564 0.78 ALDH1A1 (0.41) ALDH1A1THRBTSHRGAA
Ammonia Solution, Strong SCHEMBL7724540 0.78 TSHR (0.42) ALDH1A1THRBTSHRGAA
Hydrochloric Acid SCHEMBL28854121 0.78 ALDH1A1 (0.41) ALDH1A1THRBTSHRGAA
SCHEMBL782309 0.78 ALDH1A1 (0.41) ALDH1A1THRBTSHRGAA
SCHEMBL1494476 0.77 ALDH1A1 (0.44) ALDH1A1THRBTSHR
SCHEMBL278099 0.77 ALDH1A1 (0.44) ALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 US disclosed
US-20200223984-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2020-07-16 US disclosed
US-10696795-B2 Photoaligning materials Rolic Technologies AG (CH) 2020-06-30 US disclosed
EP-3374467-B1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS ROLIC TECH AG (CH) 2020-04-15 EP disclosed
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group ROLIC AG (CH) 2019-02-19 US disclosed
US-20180319939-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2018-11-08 US disclosed
US-20180320072-A1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS Rolic Technologies AG (CH) 2018-11-08 US disclosed
EP-3374416-A1 PHOTOALIGNMENT MATERIALS ROLIC Technologies AG (CH) 2018-09-19 EP disclosed
EP-3374467-A1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS ROLIC Technologies AG (CH) 2018-09-19 EP disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2010-02-25 US disclosed
EP-2152660-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP Rolic AG (CH) 2010-02-17 EP disclosed
EP-2144951-A1 THERMALLY STABLE ALIGNMENT MATERIALS Rolic AG (CH) 2010-01-20 EP disclosed
WO-2008145225-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2008-12-04 WO disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
EP-1966119-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2008-09-10 EP disclosed
EP-1860094-A1 Photocrosslinkable materials Rolic AG (CH) 2007-11-28 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group DDC, ALAD, DYNC1LI1 ALDH1A1 97/4885THRB 4854/4885TSHR 4828/4885
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP DDC, ALAD, DYNC1LI1 ALDH1A1 97/4885THRB 4854/4885TSHR 4828/4885
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD ALDH1A1 313/4885THRB 4212/4885TSHR 3933/4885
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS PARG, PARN, PUF60 ALDH1A1 2166/4885THRB 4108/4885TSHR 4598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.