Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656070 | 0.97 | ALDH1A1 (0.38) | PPARGPPARAMTNR1AMTNR1BRYR2 | |
| SCHEMBL8655768 | 0.90 | ALDH1A1 (0.39) | HTTMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL8657516 | 0.88 | LMNA (0.33) | HTTALDH1A1LMNA | |
| SCHEMBL8658039 | 0.88 | PLAU (0.35) | HTTL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8408765 | 0.86 | DRD2 (0.37) | HTTMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL8661839 | 0.84 | PPARD (0.38) | PPARGPPARAHTTLMNASMN1; SMN2 | |
| SCHEMBL8660335 | 0.84 | PPARD (0.36) | HTTMAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8992644 | 0.84 | HTR1A (0.33) | PPARAHTTMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8656652 | 0.83 | MCL1 (0.37) | HTTMAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8658134 | 0.82 | FFAR4 (0.37) | PPARAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |