Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656805 | 0.91 | HTR7 (0.38) | HTR7TRPV6CHRM2CHRM1KDM4E | |
| SCHEMBL8659155 | 0.89 | CYP1A2 (0.37) | HTR7SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL8659538 | 0.88 | HTR7 (0.36) | HTR7TRPV6SIGMAR1RECQLSMN1; SMN2 | |
| SCHEMBL8659427 | 0.87 | HTR7 (0.41) | HTR7SIGMAR1CHRM2CHRM1 | |
| SCHEMBL8659391 | 0.85 | HTR7 (0.39) | HTR7SIGMAR1SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL8655132 | 0.84 | ITGB3 (0.33) | ITGB3ITGA2BALOX15RECQLSMN1; SMN2 | |
| SCHEMBL8659270 | 0.84 | HTR7 (0.36) | HTR7ITGB3ITGA2BSIGMAR1CHRM2 | |
| SCHEMBL8655668 | 0.84 | SMN1; SMN2 (0.44) | HTR7SMN1; SMN2ALDH1A1 | |
| SCHEMBL8658295 | 0.83 | ALDH1A1 (0.33) | HTR7RECQLSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8655682 | 0.82 | S1PR1 (0.32) | RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |