Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | AOC2 | O75106 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591968 | 0.76 | CA2 (0.44) | NISCHALOX5CA2 | |
| SCHEMBL5023943 | 0.68 | HPGD (0.39) | HPGDTSHRGABRA1GABRB2NISCH | |
| SCHEMBL860446 | 0.66 | HPGD (0.59) | HPGDTSHRNISCHAOC2MAOA | |
| SCHEMBL29974170 | 0.66 | HPGD (0.59) | HPGDTSHRNISCHAOC2MAOA | |
| SCHEMBL5015240 | 0.66 | MMP3 (0.42) | HPGDTSHRGABRA1GABRB2NISCH | |
| SCHEMBL7313976 | 0.63 | AOC2 (0.41) | HPGDTSHRGABRA1GABRB2NISCH | |
| Hydrochloric Acid SCHEMBL10599677 | 0.62 | AOC2 (0.43) | HPGDTSHRGABRA1GABRB2NISCH | |
| Hydrochloric Acid SCHEMBL10598707 | 0.62 | AOC2 (0.43) | HPGDTSHRGABRA1GABRB2NISCH | |
| SCHEMBL7748074 | 0.62 | CA2 (0.44) | HPGDTSHRNISCHAOC2MAOA | |
| Hydrochloric Acid SCHEMBL28624862 | 0.62 | AOC2 (0.43) | HPGDTSHRNISCHAOC2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1101815-C | 3 -amidochromanylsulfonyl (thio) ureas, processes for their preparation, their use, and pharmaceutical preparations comprising them | HOECHST AG (DE) | 2003-02-19 | — | — | CN | disclosed |
| US-5849755-A | 3-amidochromanylsulfonyl(thio)ureas, processes for their preparation, their use, and pharmaceutical preparations comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5849755-A | 3-amidochromanylsulfonyl(thio)ureas, processes for their preparation, their use, and pharmaceutical preparations comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5849755-A | 3-amidochromanylsulfonyl(thio)ureas, processes for their preparation, their use, and pharmaceutical preparations comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| CN-1182741-A | 3 -amidochromanylsulfonyl (thio) ureas, processes for their preparation, their use, and pharmaceutical preparations comprising them | HOECHST AG (DE) | 1998-05-27 | — | — | CN | disclosed |