Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660410 | 0.92 | POLB (0.44) | POLBALDH1A1NPSR1TP53MEN1 | |
| SCHEMBL6858153 | 0.88 | ITGA4 (0.38) | ALDH1A1TP53MEN1KMT2ANPC1 | |
| SCHEMBL8660379 | 0.86 | SLC6A1 (0.34) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8662098 | 0.85 | PIK3CD (0.34) | POLBALDH1A1TSHRHIF1A | |
| SCHEMBL8662717 | 0.85 | MTNR1B (0.37) | POLBALDH1A1TP53MEN1KMT2A | |
| SCHEMBL12248426 | 0.84 | POLB (0.46) | POLBALDH1A1NPSR1TP53MEN1 | |
| SCHEMBL8661457 | 0.82 | HPGD (0.35) | ALDH1A1HIF1ASLC6A12 | |
| SCHEMBL8661019 | 0.82 | LMNA (0.38) | SLC6A12 | |
| SCHEMBL8662972 | 0.81 | PIK3CD (0.45) | ALDH1A1NPSR1MEN1KMT2ANPC1 | |
| SCHEMBL8661348 | 0.81 | ALDH1A1 (0.34) | POLBALDH1A1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714606-A | OLIGONUCLEOTIDE HAVING RECEPTOR BINDING SITES; ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS, MEDICAL DIAGNOSIS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-03 | — | — | US | disclosed |