Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | PIR | O00625 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140104 | 0.92 | RORC (0.49) | RORCARADAMTS4MMP13NPC1 | |
| SCHEMBL6140394 | 0.85 | RORC (0.44) | RORCARADAMTS4MMP13NPC1 | |
| SCHEMBL6140238 | 0.85 | RORC (0.44) | RORCARADAMTS4MMP13NPC1 | |
| SCHEMBL6140119 | 0.82 | LMNA (0.44) | RORCADAMTS4MMP13MAOBKMT2A | |
| SCHEMBL6140274 | 0.81 | RORC (0.45) | RORCARADAMTS4MMP13NPC1 | |
| SCHEMBL6140544 | 0.81 | RORC (0.45) | RORCARADAMTS4MMP13NPC1 | |
| SCHEMBL6140482 | 0.80 | TSHR (0.44) | RORCARADAMTS4MMP13MAOB | |
| SCHEMBL6140591 | 0.80 | TSHR (0.44) | RORCARADAMTS4MMP13MAOB | |
| SCHEMBL6140400 | 0.80 | LMNA (0.47) | RORCAPPARADAMTS4MMP13 | |
| SCHEMBL6140061 | 0.79 | ALDH1A1 (0.53) | NPC1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847218-A | Sulfonium salts and chemically amplified positive resist compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |