SCHEMBL866227

SCHEMBL866227

O=C(O)CCC(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.38
EGLN1 Q9GZT9 2/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
THRB P10828 2/20 0.37
ALDH1A1 P00352 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
NAALAD2 Q9Y3Q0 1/20 0.34
TSHR P16473 2/20 0.33
NFKB1 P19838 1/20 0.33
PMP22 Q01453 1/20 0.33
FFAR3 O14843 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
ESR1 P03372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL935232 0.93 THRB (0.41) LMNAEGLN1ALKBH5SUCNR1THRB
SCHEMBL5483523 0.91 THRB (0.44) LMNAEGLN1ALKBH5SUCNR1THRB
SCHEMBL5490761 0.91 THRB (0.44) LMNAEGLN1ALKBH5SUCNR1THRB
SCHEMBL934065 0.91 THRB (0.44) LMNAEGLN1ALKBH5SUCNR1THRB
SCHEMBL1827086 0.91 THRB (0.44) LMNAEGLN1ALKBH5SUCNR1THRB
SCHEMBL5488963 0.91 THRB (0.44) LMNAEGLN1ALKBH5SUCNR1THRB
SCHEMBL5490493 0.91 THRB (0.44) LMNAEGLN1ALKBH5SUCNR1THRB
SCHEMBL5485779 0.91 THRB (0.44) LMNAEGLN1ALKBH5SUCNR1THRB
SCHEMBL1828702 0.91 THRB (0.44) LMNAEGLN1ALKBH5SUCNR1THRB
SCHEMBL1519575 0.91 THRB (0.44) LMNAEGLN1ALKBH5SUCNR1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4527829-A1 PROCESS FOR THE PURIFICATION OF PERFLUOROALKYL ACIDS Chiron AS (NO) 2025-03-26 EP claimed
WO-2023107629-A1 MATERIALS FOR THE CAPTURE OF SUBSTANCES Membrion, Inc. (US) 2023-06-15 WO claimed
CN-110770271-B Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2023-04-18 CN claimed
EP-3635022-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME Etna-Tec, Ltd (US) 2020-04-15 EP claimed
CN-110770271-A Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2020-02-07 CN claimed
WO-2018213850-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME ETNA-TEC, LTD (US) 2018-11-22 WO claimed
US-20180334416-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ETNA-TEC, LTD. 2018-11-22 US claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-12576297-B2 Apparatus and methods for sonochemical degradation of per- and polyfluoroalkyl substances THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-17 US disclosed
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
EP-4686757-A1 INHIBITORS OF EXPRESSION AND/OR FUNCTION e-therapeutics PLC (GB) 2026-02-04 EP disclosed
US-12392782-B2 Characterization of protein binding to per- and polyfluoroalkyl substances NORTH CAROLINA STATE UNIVERSITY (US) 2025-08-19 US disclosed
EP-3635022-B1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME ETNA TEC LTD (US) 2025-05-21 EP disclosed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP disclosed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO disclosed
US-6264929-B1 COMPLEX WELLA AKTIENGESELLSCHAFT (DE) 2001-07-24 US disclosed
EP-0943312-A2 Hair- care products with fluorinated acids and polymers Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product CD38, PARP9, MCCC2 LMNA 1936/4885EGLN1 271/4885ALKBH5 68/4885
US-12576297-B2 Apparatus and methods for sonochemical degradation of per- and polyfluoroalkyl substances PFAS, PIEZO1, UFL1 LMNA 1329/4885EGLN1 993/4885ALKBH5 2079/4885
US-20180334416-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ALKBH3, FTO, ALK LMNA 1234/4885EGLN1 201/4885ALKBH5 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.