SCHEMBL8663240

SCHEMBL8663240

[O-][S+](c1[nH]c(-c2ccc(Cl)cc2)c(Br)c1Br)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.31
GCGR P47871 1/20 0.31
MAPK14 Q16539 1/20 0.31
PTGS1 P23219 1/20 0.31
MAPT P10636 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8665123 0.82 PTGS2 (0.33) PTGS2PTGS1
SCHEMBL8662395 0.78 GYS1 (0.30)
SCHEMBL8662416 0.75 GCGR (0.33) PTGS2GCGRMAPK14PTGS1MAPT
SCHEMBL8662865 0.70 MAPT (0.35) PTGS2GCGRMAPK14PTGS1MAPT
SCHEMBL9254221 0.69 GCGR (0.32) GCGRMAPK14MAPT
SCHEMBL8662090 0.69 GCGR (0.33) GCGRMAPK14MAPT
SCHEMBL8798325 0.67 PSD (0.34) GCGRMAPK14NPSR1
SCHEMBL8668183 0.67 PTGS2 (0.35) PTGS2GCGRMAPK14PTGS1
SCHEMBL7782939 0.66 PSD (0.31)
SCHEMBL7651489 0.65 LMNA (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5739155-A Haloalkylthio,-sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents AMERICAN CYANAMID CO. (US) 1998-04-14 US disclosed
EP-0549866-B1 Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents AMERICAN CYANAMID CO (US) 1997-08-13 EP disclosed
US-5484807-A Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents BASF AKTIENGESELLSCHAFT 1996-01-16 US disclosed
US-5468877-A FOR PROTECTING CROPS AMERICAN CYANAMID COMPANY (US) 1995-11-21 US disclosed
US-5306827-A Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents AMERICAN CYANAMID COMPANY (US) 1994-04-26 US disclosed
US-5284863-A Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole fungicidal agents AMERICAN CYANAMID COMPANY (US) 1994-02-08 US disclosed
EP-0549866-A1 Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents AMERICAN CYANAMID COMPANY (US) 1993-07-07 EP disclosed