Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486957 | 0.87 | ALDH1A1 (0.35) | ALDH1A1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL8484527 | 0.87 | HPGD (0.37) | ALDH1A1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL8862152 | 0.81 | MAPT (0.41) | ALDH1A1ALOX15TSHRBRD4KMT2A | |
| SCHEMBL8554066 | 0.79 | TRPA1 (0.35) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL8155272 | 0.78 | NPC1 (0.34) | ALDH1A1LMNABRD4KAT2BMEN1 | |
| SCHEMBL8343534 | 0.77 | APLNR (0.43) | ALDH1A1ALOX15POLBMEN1KMT2A | |
| SCHEMBL6603431 | 0.72 | HCAR1 (0.48) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL8664609 | 0.71 | SETDB1 (0.37) | LMNAMEN1KMT2ABRD9 | |
| SCHEMBL8660658 | 0.70 | SETDB1 (0.39) | LMNATSHRHTTBRD9 | |
| SCHEMBL8492895 | 0.69 | BRD9 (0.35) | ALDH1A1LMNAMAPK1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999011129-A1 | ENANTIOMERICALLY ENRICHED COMPOSITIONS AND THEIR PESTICIDAL USE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-11 | — | — | WO | disclosed |