Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076284 | 0.76 | NOS2 (0.38) | TDP1TDP2NSD2ABL1PLCG1 | |
| SCHEMBL581013 | 0.73 | ALOX15 (0.41) | TDP1CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL29476089 | 0.73 | ALOX15 (0.41) | TDP1CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL3677765 | 0.72 | PABPC1 (0.33) | TDP1TDP2NSD2ABL1PLCG1 | |
| SCHEMBL310818 | 0.70 | ALDH1A1 (0.42) | TDP1TDP2NSD2ABL1PLCG1 | |
| SCHEMBL7483193 | 0.67 | ALOX15 (0.32) | TDP1ALDH1A1ALOX15 | |
| SCHEMBL7817043 | 0.66 | ALDH1A1 (0.45) | TDP1TDP2NSD2ABL1PLCG1 | |
| SCHEMBL27887930 | 0.65 | HTR2B (0.40) | TDP1KMT2APDE3BPDE3AALOX15 | |
| SCHEMBL311088 | 0.64 | TDP2 (0.58) | TDP1TDP2NSD2ABL1PLCG1 | |
| SCHEMBL263099 | 0.64 | ALOX15 (0.50) | TDP1CES1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840904-A | Fluoro-pyridine-2,3-dicarboxylic anhydrides which are intermediates for herbicidal pyridine-2,3-dicarboximides | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |