Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 9/20 | 0.34 |
| ▸ | HTR1A | P08908 | 8/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | WNT3 | P56703 | 2/20 | 0.34 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSC | P53634 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712879 | 0.95 | HTR1A (0.37) | HTR7HTR1AWNT3SFRP1CCR3 | |
| SCHEMBL8665880 | 0.86 | UTS2R (0.39) | AKT1CTSBCTSKCTSLMTNR1A | |
| SCHEMBL8664869 | 0.85 | SMPD3 (0.38) | SMPD3MTNR1AMTNR1B | |
| SCHEMBL8666092 | 0.84 | UTS2R (0.39) | AKT1CTSBCTSKCTSLMTNR1A | |
| SCHEMBL8485533 | 0.83 | NPSR1 (0.42) | CCR3DRD2 | |
| SCHEMBL8665515 | 0.82 | CCR3 (0.41) | HTR7HTR1ACCR3MTNR1AMTNR1B | |
| SCHEMBL8713180 | 0.82 | CKS1B (0.41) | DRD2 | |
| SCHEMBL8501233 | 0.81 | NPSR1 (0.36) | DRD2 | |
| SCHEMBL8484454 | 0.81 | NPSR1 (0.42) | CCR3DRD2 | |
| SCHEMBL8593677 | 0.81 | ALDH1A1 (0.36) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |