Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSC | P53634 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | SFRP1 | Q8N474 | 4/20 | 0.34 |
| ▸ | WNT3 | P56703 | 3/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712881 | 0.95 | POLB (0.35) | POLBSFRP1WNT3HTR7DRD2 | |
| SCHEMBL8665881 | 0.87 | DRD2 (0.37) | AKT1POLBCTSBCTSKCTSL | |
| SCHEMBL8664872 | 0.85 | SMPD2 (0.37) | POLBSMPD3 | |
| SCHEMBL8666097 | 0.84 | DRD2 (0.36) | AKT1POLBCTSBCTSKCTSL | |
| SCHEMBL8593680 | 0.82 | POLB (0.42) | POLBDRD2DRD4DRD3 | |
| SCHEMBL8665519 | 0.82 | CCR3 (0.40) | HTR7DRD2HTR1AHTR6 | |
| SCHEMBL8501237 | 0.82 | MTTP (0.36) | POLBDRD2DRD4DRD3 | |
| SCHEMBL8713182 | 0.81 | CKS1B (0.38) | POLBDRD2HTR1ADRD4DRD3 | |
| SCHEMBL8665528 | 0.80 | CCR3 (0.40) | HTR7DRD2HTR1AHTR6 | |
| SCHEMBL8501050 | 0.79 | MTTP (0.36) | POLBDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |