Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2494854 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KDM4EADORA1ADORA2ASMN1; SMN2 | |
| SCHEMBL8664266 | 0.80 | MAPT (0.41) | POLBNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8663197 | 0.79 | NR1H4 (0.41) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL490794 | 0.78 | RELA (0.40) | GAANPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL2497219 | 0.77 | PARP10 (0.40) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8667011 | 0.77 | ABL1 (0.46) | POLBGAANPC1RAB9AALDH1A1 | |
| SCHEMBL491196 | 0.75 | RAB9A (0.43) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8665435 | 0.75 | MAPT (0.42) | POLBNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8665416 | 0.75 | NPC1 (0.44) | GAANPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11268438 | 0.75 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1KDM4EBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792589-A | ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |