Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666981 | 0.86 | MAPT (0.39) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL8667184 | 0.84 | CYP1A2 (0.38) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL491196 | 0.83 | RAB9A (0.43) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8668248 | 0.77 | ALDH1A1 (0.46) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL1877506 | 0.77 | TAAR1 (0.40) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL491300 | 0.76 | SLC6A3 (0.39) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL8663506 | 0.71 | CYP1A2 (0.46) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL8665969 | 0.71 | CYP2A6 (0.43) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL8665808 | 0.70 | CYP1A2 (0.45) | KDM4EMEN1KMT2AALDH1A1CYP2A6 | |
| SCHEMBL2689653 | 0.70 | WDR5 (0.37) | MAPTMAPK1KDM4EALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792589-A | ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |