Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666490 | 0.90 | KMT2A (0.35) | ROCK2KMT2ATOP2AHCRTR1 | |
| SCHEMBL8093681 | 0.84 | NOTUM (0.45) | ROCK2TOP2AHCRTR1HCRTR2 | |
| SCHEMBL6508236 | 0.81 | ROCK2 (0.38) | ROCK2KMT2AATMTOP2AHCRTR1 | |
| SCHEMBL8666480 | 0.80 | DRD2 (0.37) | KMT2AHCRTR1HCRTR2 | |
| SCHEMBL8666484 | 0.79 | GRM2 (0.41) | HCRTR1HCRTR2EPHX2GRIN1GRIN2B | |
| SCHEMBL5827283 | 0.76 | MEN1 (0.46) | KMT2ANPC1RAB9A | |
| SCHEMBL8089006 | 0.70 | TSHR (0.36) | RXRAGRIN1GRIN2B | |
| SCHEMBL7806313 | 0.70 | ALDH1A1 (0.58) | KMT2ANPC1RAB9A | |
| SCHEMBL30158663 | 0.69 | KMT2A (0.53) | KMT2ANPC1RAB9A | |
| SCHEMBL6510658 | 0.69 | ROCK2 (0.53) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022976-A | Process for the production of 5-hydroxyoxazolidinones | ZENECA LIMITED | 2000-02-08 | — | — | US | disclosed |
| EP-0880510-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028138-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |