Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093681 | 0.88 | NOTUM (0.45) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8666484 | 0.82 | GRM2 (0.41) | DRD2DRD3MCHR1GRM2HCRTR1 | |
| SCHEMBL8096256 | 0.80 | ROCK2 (0.39) | HCRTR1HCRTR2KMT2A | |
| SCHEMBL5827283 | 0.77 | MEN1 (0.46) | DRD2DRD3NOTUMKMT2A | |
| SCHEMBL8666490 | 0.76 | KMT2A (0.35) | DRD2DRD3KCNH2HCRTR1FADS1 | |
| SCHEMBL8670343 | 0.74 | DRD2 (0.39) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8556168 | 0.73 | DRD2 (0.44) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8556361 | 0.73 | DRD2 (0.44) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8787181 | 0.72 | FFAR4 (0.49) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8788951 | 0.71 | NOTUM (0.42) | DRD2DRD3KCNH2NOTUMMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705456-A | AZETIDIN-2-ONES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |