Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666713 | 0.78 | MAPT (0.43) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8665551 | 0.78 | MEN1 (0.43) | ALDH1A1LMNAMAPTKMT2ARAB9A | |
| SCHEMBL8997939 | 0.78 | L3MBTL1 (0.43) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8664507 | 0.75 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8663214 | 0.75 | MAPT (0.40) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8907017 | 0.73 | ALDH1A1 (0.47) | ALDH1A1LMNACYP2D6CYP2C9MAPT | |
| SCHEMBL8440417 | 0.72 | ALDH1A1 (0.71) | ALDH1A1LMNASLC6A5SLC6A9SMN1; SMN2 | |
| SCHEMBL9630885 | 0.72 | C1R (0.43) | ALDH1A1LMNAMAPTKMT2AHTT | |
| SCHEMBL6189223 | 0.71 | CTSB (0.50) | ALDH1A1LMNASMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL8665467 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852006-A | N-aminoalkyl-substituted nitrogen-containing six membered heterocyclic compounds | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5574030-A | INHIBITING URINARY CONTRACTION, HETEROCYCLIC DIAMINES | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |