Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997939 | 0.83 | L3MBTL1 (0.43) | ALDH1A1LMNAMAPTGAAPRKDC | |
| SCHEMBL8666713 | 0.80 | MAPT (0.43) | ALDH1A1LMNAMAPTGAAPRKDC | |
| SCHEMBL8665551 | 0.80 | MEN1 (0.43) | ALDH1A1LMNAMAPTPRKDCL3MBTL1 | |
| SCHEMBL8663214 | 0.77 | MAPT (0.40) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL8667066 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL8665467 | 0.72 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTGAAL3MBTL1 | |
| SCHEMBL2432403 | 0.71 | GPR3 (0.41) | ALDH1A1TSHR | |
| SCHEMBL5778162 | 0.71 | HSD11B1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL8416356 | 0.70 | HSD11B1 (0.42) | — | |
| SCHEMBL4287156 | 0.69 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852006-A | N-aminoalkyl-substituted nitrogen-containing six membered heterocyclic compounds | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5574030-A | INHIBITING URINARY CONTRACTION, HETEROCYCLIC DIAMINES | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |