Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500612 | 0.92 | MEN1 (0.44) | L3MBTL1BCHEMEN1TSHRKMT2A | |
| SCHEMBL8675063 | 0.77 | L3MBTL1 (0.42) | L3MBTL1MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL8480408 | 0.76 | TMEM97 (0.38) | L3MBTL1BCHEMEN1TSHRKMT2A | |
| SCHEMBL8485150 | 0.68 | L3MBTL1 (0.41) | L3MBTL1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL8480413 | 0.68 | TMEM97 (0.35) | L3MBTL1HTR2BOPRK1HTR2A | |
| SCHEMBL8677227 | 0.67 | HTR1A (0.46) | MEN1TSHRKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10485607 | 0.67 | ACHE (0.59) | DRD2DRD3OPRM1OPRK1OPRL1 | |
| SCHEMBL5633429 | 0.67 | ACHE (0.59) | DRD2DRD3OPRM1OPRK1OPRL1 | |
| SCHEMBL8667996 | 0.66 | UTS2R (0.47) | DRD2HTR7 | |
| SCHEMBL8483370 | 0.66 | MTR (0.40) | MEN1TSHRKMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |