Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480408 | 0.90 | TMEM97 (0.38) | L3MBTL1MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL8485120 | 0.86 | TSHR (0.36) | DRD2MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL8480927 | 0.86 | NPSR1 (0.41) | L3MBTL1DRD2MEN1TSHRKMT2A | |
| SCHEMBL8668070 | 0.83 | MEN1 (0.35) | DRD2MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL8485591 | 0.83 | NPY1R (0.41) | MEN1TSHRKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8503791 | 0.79 | TSHR (0.37) | DRD2MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL8479245 | 0.79 | SCN1A (0.39) | MEN1KMT2A | |
| SCHEMBL8669685 | 0.78 | NPSR1 (0.42) | DRD2NPSR1 | |
| SCHEMBL8487923 | 0.77 | SCN1A (0.38) | MEN1KMT2A | |
| SCHEMBL8485150 | 0.77 | L3MBTL1 (0.41) | L3MBTL1DRD2SLC6A4MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1729-H | Method for preparing compounds employing solid phase synthesis and novel linker-resin | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |