Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485122 | 0.95 | DRD2 (0.39) | DRD2DRD4DRD3BCHEACHE | |
| SCHEMBL8503794 | 0.93 | DRD2 (0.38) | DRD2DRD4DRD3BCHEACHE | |
| SCHEMBL8675068 | 0.84 | L3MBTL1 (0.42) | DRD2DRD4DRD3KMT2AKDM4E | |
| SCHEMBL8480412 | 0.84 | DRD2 (0.37) | DRD2DRD4DRD3KMT2AKDM4E | |
| SCHEMBL8480929 | 0.83 | DRD2 (0.44) | DRD2DRD4DRD3KMT2AKDM4E | |
| SCHEMBL8669688 | 0.82 | DRD2 (0.39) | DRD2DRD4DRD3KDM4ENAMPT | |
| SCHEMBL8485593 | 0.80 | NPY1R (0.40) | DRD2DRD4DRD3LMNAGAA | |
| SCHEMBL8664324 | 0.80 | NPY1R (0.35) | LMNAPOLBGAANPSR1 | |
| SCHEMBL8714745 | 0.80 | CHRM1 (0.41) | DRD2DRD4DRD3KMT2AHPGD | |
| SCHEMBL8664248 | 0.79 | PSEN1 (0.34) | LMNAPOLBGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |