Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672106 | 0.87 | LMNA (0.37) | DPP4ALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL8667689 | 0.79 | GPR88 (0.35) | MC4RALDH1A1USP2MEN1KMT2A | |
| SCHEMBL8668716 | 0.78 | FKBP1A (0.39) | TSHRHSD17B10HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8666883 | 0.74 | AGTR2 (0.34) | HPGDALDH1A1KMT2A | |
| SCHEMBL8670326 | 0.74 | AGTR2 (0.34) | HPGDALDH1A1KMT2A | |
| SCHEMBL8666885 | 0.72 | ACE (0.46) | DPP4 | |
| SCHEMBL8667007 | 0.72 | POLB (0.44) | HPGDALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8666332 | 0.72 | ACE (0.54) | DPP4ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8671876 | 0.71 | SIGMAR1 (0.37) | TLR2TLR1 | |
| SCHEMBL8670628 | 0.71 | SIGMAR1 (0.41) | TSHRALDH1A1L3MBTL1TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |