SCHEMBL8668359

SCHEMBL8668359

CN(C(=O)OC(C)(C)C)c1[c]cccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.40
BRD4 O60885 2/20 0.38
MEN1 O00255 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
GPR119 Q8TDV5 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
NCOR2 Q9Y618 1/20 0.34
HTR2C P28335 1/20 0.34
SLC6A4 P31645 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
CREBBP Q92793 1/20 0.33
BCHE P06276 1/20 0.33
MALT1 Q9UDY8 1/20 0.32
MMP13 P45452 1/20 0.32
AKT1 P31749 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2535686 0.81 TSHR (0.42) MEN1RAB9AKMT2ANPSR1L3MBTL1
SCHEMBL2533555 0.77 LMNA (0.41) MEN1RAB9AKMT2ANPSR1HDAC1
SCHEMBL2536241 0.77 LMNA (0.41) MEN1RAB9AKMT2ANPSR1L3MBTL1
SCHEMBL16294301 0.75 RAB9A (0.36) MEN1RAB9AKMT2ANPSR1POLB
SCHEMBL95841 0.75 ALDH1A1 (0.39) MEN1RAB9AKMT2APDK2ALDH1A1
SCHEMBL21084775 0.75 PAX8 (0.46) PAX8BRD4MEN1RAB9AKMT2A
SCHEMBL2533235 0.75 ALDH1A1 (0.44) L3MBTL1LMNAALDH1A1TSHRTDP1
SCHEMBL7200107 0.74 RAB9A (0.57) PAX8BRD4MEN1RAB9AKMT2A
SCHEMBL1416233 0.74 ALOX5 (0.34) KMT2AL3MBTL1POLBCYP2C19ALDH1A1
SCHEMBL8668409 0.74 ALDH1A1 (0.47) PAX8RAB9AKMT2AL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101677540-A Herbicidally effective composition EIKE HUPE 2010-03-24 CN disclosed
CN-1225471-C Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 2005-11-02 CN disclosed
CN-1137120-C 5, 11-dihydrodibenzo [ b, e ] [1,4] oxazepine * derivatives and pharmaceutical compositions containing the same ֮����ʽ���� 2004-02-04 CN disclosed
US-5750552-A ANTIULCER AGENTS ARAX CO., LTD. (JP) 1998-05-12 US disclosed
CN-1176645-A Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 1998-03-18 CN disclosed
EP-0736527-A1 Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer ARAX CO., LTD. (JP) 1996-10-09 EP disclosed