Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.66 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.66 |
| ▸ | NSD2 | O96028 | 1/20 | 0.62 |
| ▸ | G6PD | P11413 | 1/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.62 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | THRB | P10828 | 4/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isosulfan Blue Inner Salt SCHEMBL30876833 | 1.00 | HSP90AA1 (0.66) | HSP90AA1TLR9NSD2G6PDCDK5 | |
| Isosulfan Blue Inner Salt SCHEMBL29683989 | 0.99 | HSP90AA1 (0.64) | HSP90AA1TLR9NSD2G6PDCDK5 | |
| Isosulfan Blue Inner Salt SCHEMBL31244567 | 0.99 | HSP90AA1 (0.64) | HSP90AA1TLR9NSD2G6PDCDK5 | |
| Isosulfan Blue Inner Salt SCHEMBL30876834 | 0.94 | HSP90AA1 (0.66) | HSP90AA1TLR9NSD2G6PDCDK5 | |
| Isosulfan Blue Inner Salt SCHEMBL180549 | 0.94 | HSP90AA1 (0.66) | HSP90AA1TLR9NSD2G6PDCDK5 | |
| SCHEMBL4813305 | 0.92 | HSP90AA1 (0.66) | HSP90AA1TLR9NSD2G6PDCDK5 | |
| Water SCHEMBL185743 | 0.91 | HSP90AA1 (0.64) | HSP90AA1TLR9NSD2G6PDCDK5 | |
| SCHEMBL29499146 | 0.91 | HSP90AA1 (0.64) | HSP90AA1TLR9NSD2G6PDCDK5 | |
| Water SCHEMBL5921888 | 0.90 | HSP90AA1 (0.63) | HSP90AA1TLR9NSD2G6PDCDK5 | |
| SCHEMBL25506709 | 0.90 | HSP90AA1 (0.62) | HSP90AA1TLR9NSD2G6PDCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347013-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2020-11-05 | — | — | US | claimed |
| US-10590071-B2 | Process for the preparation of isosulfan blue | APICORE US LLC (US) | 2020-03-17 | — | — | US | claimed |
| US-10562847-B2 | Method for preparation of isosulfan blue | Beloteca Investment Fund 1, LLC (US) | 2020-02-18 | — | — | US | claimed |
| US-10464888-B2 | Process for the preparation of isosulfan blue | APICORE US LLC (US) | 2019-11-05 | — | — | US | claimed |
| US-20190225626-A1 | ISOSULFAN BLUE, ITS CRYSTALLINE FORM AND PROCESS FOR PREPARATION THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2019-07-25 | — | — | US | claimed |
| US-20190177269-A1 | Process for the preparation of Isosulfan Blue | APICORE US LLC (US) | 2019-06-13 | — | — | US | claimed |
| US-20190152903-A1 | METHOD FOR PREPARATION OF ISOSULFAN BLUE | Beloteca Investment Fund 1, LLC (US) | 2019-05-23 | — | — | US | claimed |
| US-20180057454-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2018-03-01 | — | — | US | claimed |
| WO-2018008040-A1 | ISOSULFAN BLUE, ITS CRYSTALLINE FORM AND PROCESS FOR PREPARATION THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2018-01-11 | — | — | WO | claimed |
| WO-2017218764-A1 | METHOD FOR PREPARATION OF ISOSULFAN BLUE | BELOTECA, INC. (US) | 2017-12-21 | — | — | WO | claimed |
| US-20160221936-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2016-08-04 | — | — | US | claimed |
| US-9353050-B2 | Process for preparation of isosulfan blue | APICORE US LLC (US) | 2016-05-31 | — | — | US | claimed |
| US-8969616-B2 | Process for preparation of isosulfan blue | APICORE US LLC (US) | 2015-03-03 | — | — | US | claimed |
| US-20130310600-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2013-11-21 | — | — | US | claimed |
| US-20120078007-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2012-03-29 | — | — | US | claimed |
| US-20100094044-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2010-04-15 | — | — | US | claimed |
| US-7662992-B2 | Process for preparation of isosulfan blue | APICORE, LLC (US) | 2010-02-16 | — | — | US | claimed |
| US-20080293963-A1 | PROCESS FOR PREPARATION ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-27 | — | — | US | claimed |
| US-20080281127-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-13 | — | — | US | claimed |
| US-12595228-B2 | Process for synthesizing triarylmethane sulfone compounds | PROVEPHARM LIFE SOLUTIONS (FR) | 2026-04-07 | — | — | US | disclosed |
| EP-4132905-B1 | PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS | PROVEPHARM LIFE SOLUTIONS (FR) | 2024-05-15 | — | — | EP | disclosed |
| EP-4132906-B1 | PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS | PROVEPHARM LIFE SOLUTIONS (FR) | 2024-05-15 | — | — | EP | disclosed |
| EP-4361127-A2 | PROCESS FOR THE SYNTHESIS OF SULFONATED TRIARYLMETHANE COMPOUNDS | Provepharm Life Solutions (FR) | 2024-05-01 | — | — | EP | disclosed |
| US-20230348372-A1 | PROCESS FOR SYNTHESIZING TRIARYLMETHANE SULFONE COMPOUNDS | PROVEPHARM LIFE SOLUTIONS (FR) | 2023-11-02 | — | — | US | disclosed |
| US-20230159444-A1 | PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS | PROVEPHARM LIFE SOLUTIONS (FR) | 2023-05-25 | — | — | US | disclosed |
| US-20230159444-A1 | PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS | PROVEPHARM LIFE SOLUTIONS (FR) | 2023-05-25 | — | — | US | disclosed |
| EP-4132905-A1 | PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS | Provepharm Life Solutions (FR) | 2023-02-15 | — | — | EP | disclosed |
| EP-4132906-A1 | PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS | Provepharm Life Solutions (FR) | 2023-02-15 | — | — | EP | disclosed |
| US-20200347013-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2020-11-05 | — | — | US | disclosed |
| US-10752580-B2 | Process for preparation of isosulfan blue | APICORE US LLC (US) | 2020-08-25 | — | — | US | disclosed |
| US-10752580-B2 | Process for preparation of isosulfan blue | APICORE US LLC (US) | 2020-08-25 | — | — | US | disclosed |
| US-10723745-B2 | Isosulfan blue, its crystalline form and process for preparation thereof | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2020-07-28 | — | — | US | disclosed |
| US-10723745-B2 | Isosulfan blue, its crystalline form and process for preparation thereof | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2020-07-28 | — | — | US | disclosed |
| US-10723745-B2 | Isosulfan blue, its crystalline form and process for preparation thereof | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2020-07-28 | — | — | US | disclosed |
| US-10626086-B2 | Process for the preparation of isosulfan blue | APICORE US LLC (US) | 2020-04-21 | — | — | US | disclosed |
| US-10562847-B2 | Method for preparation of isosulfan blue | Beloteca Investment Fund 1, LLC (US) | 2020-02-18 | — | — | US | disclosed |
| US-10464888-B2 | Process for the preparation of isosulfan blue | APICORE US LLC (US) | 2019-11-05 | — | — | US | disclosed |
| US-20190225626-A1 | ISOSULFAN BLUE, ITS CRYSTALLINE FORM AND PROCESS FOR PREPARATION THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2019-07-25 | — | — | US | disclosed |
| US-20190225626-A1 | ISOSULFAN BLUE, ITS CRYSTALLINE FORM AND PROCESS FOR PREPARATION THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2019-07-25 | — | — | US | disclosed |
| US-20190225626-A1 | ISOSULFAN BLUE, ITS CRYSTALLINE FORM AND PROCESS FOR PREPARATION THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2019-07-25 | — | — | US | disclosed |
| US-20190218177-A1 | Process for the preparation of Isosulfan Blue | APICORE US LLC (US) | 2019-07-18 | — | — | US | disclosed |
| US-20190177269-A1 | Process for the preparation of Isosulfan Blue | APICORE US LLC (US) | 2019-06-13 | — | — | US | disclosed |
| US-20190152903-A1 | METHOD FOR PREPARATION OF ISOSULFAN BLUE | Beloteca Investment Fund 1, LLC (US) | 2019-05-23 | — | — | US | disclosed |
| US-20180057454-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180057454-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2018-03-01 | — | — | US | disclosed |
| WO-2018008040-A1 | ISOSULFAN BLUE, ITS CRYSTALLINE FORM AND PROCESS FOR PREPARATION THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2018-01-11 | — | — | WO | disclosed |
| WO-2017218764-A1 | METHOD FOR PREPARATION OF ISOSULFAN BLUE | BELOTECA, INC. (US) | 2017-12-21 | — | — | WO | disclosed |
| WO-2017218764-A1 | METHOD FOR PREPARATION OF ISOSULFAN BLUE | BELOTECA, INC. (US) | 2017-12-21 | — | — | WO | disclosed |
| WO-2017118882-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF ISOSULFAN BLUE | DISHMAN PHARMACEUTICALS AND CHEMICALS LTD. (IN) | 2017-07-13 | — | — | WO | disclosed |
| US-9353050-B2 | Process for preparation of isosulfan blue | APICORE US LLC (US) | 2016-05-31 | — | — | US | disclosed |
| US-8969616-B2 | Process for preparation of isosulfan blue | APICORE US LLC (US) | 2015-03-03 | — | — | US | disclosed |
| US-8969616-B2 | Process for preparation of isosulfan blue | APICORE US LLC (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130310600-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2013-11-21 | — | — | US | disclosed |
| US-20120078007-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2012-03-29 | — | — | US | disclosed |
| US-20100094044-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2010-04-15 | — | — | US | disclosed |
| US-7662992-B2 | Process for preparation of isosulfan blue | APICORE, LLC (US) | 2010-02-16 | — | — | US | disclosed |
| US-7534911-B2 | Process for the preparation of Isosulphan Blue | INNOVASSYNTH TECHNOLOGIES (INDIA) LTD. (IN) | 2009-05-19 | — | — | US | disclosed |
| US-20080293963-A1 | PROCESS FOR PREPARATION ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-27 | — | — | US | disclosed |
| US-20080293963-A1 | PROCESS FOR PREPARATION ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-27 | — | — | US | disclosed |
| US-20080281127-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-13 | — | — | US | disclosed |
| US-20080281127-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (21 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094044-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, MPST, STS | HSP90AA1 1667/4885TLR9 2190/4885NSD2 3766/4885 |
| US-12595228-B2 | Process for synthesizing triarylmethane sulfone compounds | TST, SULT1E1, SULT1A1 | HSP90AA1 3351/4885TLR9 3384/4885NSD2 1670/4885 |
| US-20200347013-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, STS, MPST | HSP90AA1 2236/4885TLR9 2359/4885NSD2 3826/4885 |
| US-20190225626-A1 | ISOSULFAN BLUE, ITS CRYSTALLINE FORM AND PROCESS FOR PREPARATION THEREOF | SI, IK, RPS4Y1 | HSP90AA1 1440/4885TLR9 4580/4885NSD2 745/4885 |
| US-10752580-B2 | Process for preparation of isosulfan blue | SI, STS, MPST | HSP90AA1 2236/4885TLR9 2359/4885NSD2 3826/4885 |
| US-10464888-B2 | Process for the preparation of isosulfan blue | SI, STS, MPST | HSP90AA1 1989/4885TLR9 2208/4885NSD2 3872/4885 |
| US-20190218177-A1 | Process for the preparation of Isosulfan Blue | SI, STS, MPST | HSP90AA1 1989/4885TLR9 2208/4885NSD2 3872/4885 |
| US-10626086-B2 | Process for the preparation of isosulfan blue | SI, STS, MPST | HSP90AA1 1989/4885TLR9 2208/4885NSD2 3872/4885 |
| US-20120078007-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, MPST, STS | HSP90AA1 1667/4885TLR9 2190/4885NSD2 3766/4885 |
| US-20160221936-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, STS, MPST | HSP90AA1 2236/4885TLR9 2359/4885NSD2 3826/4885 |
| US-20190152903-A1 | METHOD FOR PREPARATION OF ISOSULFAN BLUE | TST, MB, SI | HSP90AA1 2208/4885TLR9 3245/4885NSD2 2010/4885 |
| US-20080293963-A1 | PROCESS FOR PREPARATION ISOSULFAN BLUE | SI, STS, MPST | HSP90AA1 1506/4885TLR9 2350/4885NSD2 3601/4885 |
| US-20130310600-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, MPST, STS | HSP90AA1 1667/4885TLR9 2190/4885NSD2 3766/4885 |
| US-20180057454-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, STS, MPST | HSP90AA1 2236/4885TLR9 2359/4885NSD2 3826/4885 |
| US-10590071-B2 | Process for the preparation of isosulfan blue | SI, STS, MPST | HSP90AA1 1989/4885TLR9 2208/4885NSD2 3872/4885 |
| US-10562847-B2 | Method for preparation of isosulfan blue | TST, MB, SI | HSP90AA1 2208/4885TLR9 3245/4885NSD2 2010/4885 |
| US-10723745-B2 | Isosulfan blue, its crystalline form and process for preparation thereof | SI, IK, RPS4Y1 | HSP90AA1 1440/4885TLR9 4580/4885NSD2 745/4885 |
| US-20190177269-A1 | Process for the preparation of Isosulfan Blue | SI, STS, MPST | HSP90AA1 1989/4885TLR9 2208/4885NSD2 3872/4885 |
| US-20080281127-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, MPST, STS | HSP90AA1 1667/4885TLR9 2190/4885NSD2 3766/4885 |
| US-20230348372-A1 | PROCESS FOR SYNTHESIZING TRIARYLMETHANE SULFONE COMPOUNDS | TST, SQOR, SDHA | HSP90AA1 3349/4885TLR9 3576/4885NSD2 2467/4885 |
| US-20230159444-A1 | PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS | SQOR, SULT1E1, TST | HSP90AA1 2355/4885TLR9 1509/4885NSD2 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.