Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669070 | 0.92 | CTRB1 (0.46) | ITGB3ITGA2BTLR2CTRB1KDM4E | |
| SCHEMBL8669583 | 0.86 | CTRB1 (0.49) | ITGB3ITGA2BCTRB1TDP1SYK | |
| SCHEMBL8611915 | 0.81 | ITGB3 (0.56) | ITGB3ITGA2BCTRB1MAPTL3MBTL1 | |
| SCHEMBL8770357 | 0.81 | L3MBTL1 (0.47) | TLR2KDM4ETDP1CTSLCTSS | |
| Hydrochloric Acid SCHEMBL8612059 | 0.80 | ITGB3 (0.55) | ITGB3ITGA2BCTRB1MAPTL3MBTL1 | |
| SCHEMBL8668133 | 0.80 | SIRT2 (0.52) | ITGB3ITGA2BSIRT2SIRT1SIRT3 | |
| SCHEMBL5158241 | 0.78 | CTRB1 (0.53) | ITGB3ITGA2BCTRB1SYKCTSL | |
| SCHEMBL9001915 | 0.77 | SMN1; SMN2 (0.46) | ITGB3ITGA2BCTRB1SYKMAPT | |
| SCHEMBL8668738 | 0.76 | CTRB1 (0.52) | CTRB1SYKCTSLCTSSCTSK | |
| SCHEMBL8616713 | 0.76 | CTRB1 (0.50) | ITGB3ITGA2BCTRB1SYKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853699-A | Use of tetra azacycle complexes as x-ray diagnostic agents for the liver and gallbladder | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-29 | — | — | US | disclosed |
| EP-0794800-A1 | USE OF CHELATE COMPOUNDS AS DIAGNOSTIC AGENTS IN THE X-RAY EXAMINATION OF LIVER AND BILE DUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996016678-A1 | USE OF CHELATE COMPOUNDS AS DIAGNOSTIC AGENTS IN THE X-RAY EXAMINATION OF LIVER AND BILE DUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-06-06 | — | — | WO | disclosed |