SCHEMBL8669840

SCHEMBL8669840

CC1(C)NC([S+]([O-])Cc2ccccc2N2C(=O)c3ccccc3C2=O)=NC1=S

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 5/20 0.39
NR1H2 P55055 3/20 0.39
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8666979 0.88 MGLL (0.45) MEN1LMNAMAPTKMT2AMGLL
SCHEMBL8667152 0.80 NCF1 (0.34)
SCHEMBL8668788 0.77 ATP4A (0.30)
SCHEMBL8668509 0.75 AR (0.32)
SCHEMBL8667326 0.73 AR (0.34)
SCHEMBL8665811 0.72 PSIP1 (0.36) POLBMAPT
SCHEMBL8670141 0.70 KDM4E (0.32)
SCHEMBL8669434 0.70 ALDH1A1 (0.40) POLBMEN1LMNAMAPTKMT2A
SCHEMBL8670484 0.70 KCNK3 (0.41) POLBLMNAMAPTKMT2A
SCHEMBL8665501 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750552-A ANTIULCER AGENTS ARAX CO., LTD. (JP) 1998-05-12 US disclosed
EP-0736527-A1 Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer ARAX CO., LTD. (JP) 1996-10-09 EP disclosed