Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | RARG | P13631 | 9/20 | 0.33 |
| ▸ | RARA | P10276 | 7/20 | 0.33 |
| ▸ | RARB | P10826 | 6/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089192 | 0.84 | PGR (0.32) | PGRHSD17B1RXRARARGRARA | |
| SCHEMBL8670891 | 0.84 | PGR (0.44) | PGRRXRARARGRARARARB | |
| SCHEMBL8668855 | 0.79 | RXRA (0.34) | PGRHSD17B1RXRARARGRARA | |
| SCHEMBL8671303 | 0.78 | NPC1 (0.39) | PGRRARGRARARARB | |
| SCHEMBL8866201 | 0.77 | HDAC3 (0.39) | PGRHSD17B1RARGRARB | |
| SCHEMBL9116437 | 0.76 | HSD17B1 (0.35) | PGRHSD17B1RARGRARARARB | |
| SCHEMBL8670887 | 0.75 | PGR (0.39) | PGRRXRARARGRARARARB | |
| SCHEMBL8772692 | 0.72 | RARB (0.45) | RXRARARGRARARARBRXRB | |
| SCHEMBL9425658 | 0.70 | HSD17B1 (0.43) | HSD17B1RXRARXRBRXRG | |
| SCHEMBL13613860 | 0.68 | CYP26A1 (0.37) | PGRHSD17B1RXRARARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723620-A | Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity | ALLERGAN (US) | 1998-03-03 | — | — | US | disclosed |