Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 10/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116437 | 0.80 | HSD17B1 (0.35) | RARBRARGHSD17B1PGR | |
| SCHEMBL8866206 | 0.78 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL8671302 | 0.77 | PGR (0.38) | RARBRARGHSD17B1PGR | |
| SCHEMBL8668855 | 0.75 | RXRA (0.34) | RARBRARGHSD17B1PGR | |
| SCHEMBL9425658 | 0.73 | HSD17B1 (0.43) | HSD17B1 | |
| SCHEMBL9089192 | 0.71 | PGR (0.32) | RARBRARGHSD17B1PGR | |
| SCHEMBL3799866 | 0.70 | PARP1 (0.48) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL9425231 | 0.68 | RXRB (0.46) | HDAC4HDAC2HDAC8HSD17B1 | |
| SCHEMBL9426099 | 0.68 | RARB (0.39) | RARBRARGHSD17B1 | |
| SCHEMBL8631041 | 0.66 | RARB (0.48) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616712-A | SKIN DISORDERS; ANTICARCINOGENIC AND -INFLAMMATORY AGENTS; AUTOIMMUNE DISEASES; | ALLERGAN (US) | 1997-04-01 | — | — | US | disclosed |