Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 2/20 | 0.30 |
| ▸ | RARB | P10826 | 2/20 | 0.30 |
| ▸ | RARG | P13631 | 2/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671302 | 0.84 | PGR (0.38) | PGRRXRAHSD17B1RARARARB | |
| SCHEMBL8668855 | 0.75 | RXRA (0.34) | PGRRXRAHSD17B1RARARARB | |
| SCHEMBL8866201 | 0.71 | HDAC3 (0.39) | PGRHSD17B1RARBRARG | |
| SCHEMBL9116437 | 0.70 | HSD17B1 (0.35) | PGRHSD17B1RARARARBRARG | |
| SCHEMBL8836952 | 0.69 | RARB (0.50) | RARARARBRARG | |
| SCHEMBL8836856 | 0.69 | RARB (0.50) | RARARARBRARG | |
| SCHEMBL8670891 | 0.69 | PGR (0.44) | PGRRXRARARARARBRARG | |
| SCHEMBL9425658 | 0.66 | HSD17B1 (0.43) | RXRAHSD17B1RXRBRXRG | |
| SCHEMBL8331061 | 0.65 | RARB (0.49) | RARARARBRARG | |
| SCHEMBL8671303 | 0.64 | NPC1 (0.39) | PGRRARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514825-A | SYNTHETIC RETINOIDS | ALLERGAN, INC. (US) | 1996-05-07 | — | — | US | disclosed |