Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674164 | 0.81 | SMN1; SMN2 (0.43) | PLA2G2AAGTR1AGTR2MAPTSMN1; SMN2 | |
| SCHEMBL8671451 | 0.79 | PLA2G2A (0.50) | PLA2G2AAGTR1AGTR2ALDH1A1MEN1 | |
| SCHEMBL8501923 | 0.77 | AGTR1 (0.50) | PLA2G2AAGTR1AGTR2ACHEBRS3 | |
| SCHEMBL8670875 | 0.73 | DHODH (0.47) | NPSR1ALDH1A1SMN1; SMN2BRS3 | |
| SCHEMBL8501790 | 0.69 | PLA2G2A (0.52) | PLA2G2AAGTR1AGTR2ACHE | |
| SCHEMBL7835618 | 0.69 | BRS3 (0.52) | AGTR1AGTR2BRS3 | |
| SCHEMBL8504620 | 0.68 | BRS3 (0.54) | AGTR1AGTR2BRS3 | |
| SCHEMBL8501882 | 0.68 | MAPT (0.48) | PLA2G2AAGTR1AGTR2MAPTACHE | |
| SCHEMBL8505378 | 0.67 | PLA2G2A (0.52) | PLA2G2AAGTR1AGTR2ACHEBRS3 | |
| SCHEMBL7134084 | 0.67 | PTPN11 (0.44) | PLA2G2AAGTR1AGTR2ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817674-A | ANTIOTENSIN II RECEPTOR ANTAGONISTS | ROUSSEL UCLAF (FR) | 1998-10-06 | — | — | US | disclosed |