Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726441 | 1.00 | SLC6A4 (0.35) | SLC6A4SLC6A3DRD2SLC6A2OPRM1 | |
| SCHEMBL8676816 | 0.81 | SLC6A3 (0.34) | SLC6A4SLC6A3SLC6A2OPRM1MAOA | |
| SCHEMBL1950005 | 0.81 | OPRM1 (0.42) | SLC6A4SLC6A3SLC6A2OPRM1ALDH1A1 | |
| SCHEMBL1950007 | 0.81 | OPRM1 (0.42) | SLC6A4SLC6A3SLC6A2OPRM1ALDH1A1 | |
| SCHEMBL28702200 | 0.81 | OPRM1 (0.38) | OPRM1MAOAMAOBMEN1KMT2A | |
| SCHEMBL19207539 | 0.81 | OPRM1 (0.38) | OPRM1MAOAMAOBMEN1KMT2A | |
| SCHEMBL7198147 | 0.75 | MAOA (0.39) | SLC6A4SLC6A3DRD2SLC6A2OPRM1 | |
| SCHEMBL20876286 | 0.74 | SLC6A4 (0.40) | SLC6A4SLC6A3DRD2SLC6A2OPRM1 | |
| SCHEMBL12000524 | 0.70 | SLC6A3 (0.46) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL23270189 | 0.70 | DRD2 (0.38) | SLC6A4SLC6A3DRD2SLC6A2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849958-A | 1,4,diaryl-2-fluoro-2-butene insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |