SCHEMBL8675019

SCHEMBL8675019

CCO/N=C(/C)c1c(Cl)ccc(C(=O)c2cnn(C)c2O)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
ALDH1A1 P00352 2/20 0.32
KMT2A Q03164 1/20 0.32
POLB P06746 1/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8675021 1.00 SMN1; SMN2 (0.33) SMN1; SMN2LMNAMAPTALDH1A1KMT2A
SCHEMBL9076331 0.79 KDM4E (0.38) ALDH1A1KMT2AHPGD
SCHEMBL10729447 0.77 HTT (0.34) SMN1; SMN2LMNAMAPTALDH1A1KMT2A
SCHEMBL22945925 0.77 CNR1 (0.33) SMN1; SMN2LMNAMAPTALDH1A1KMT2A
SCHEMBL10724382 0.75 PKM (0.34) SMN1; SMN2LMNAMAPTALDH1A1KMT2A
SCHEMBL8423375 0.74 FGFR1 (0.34) SMN1; SMN2LMNAMAPTALDH1A1KMT2A
SCHEMBL9078850 0.74 KMO (0.33) SMN1; SMN2LMNAALDH1A1KMT2A
SCHEMBL9075566 0.72 ALDH1A1 (0.36) SMN1; SMN2LMNAMAPTALDH1A1KMT2A
SCHEMBL4496557 0.72 SMN1; SMN2 (0.36) SMN1; SMN2LMNAMAPTALDH1A1KMT2A
SCHEMBL4493651 0.71 KDM4E (0.32) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10338675-A None JP disclosed
JP-H10338675-A 4-BENZOYLPYRAZOLE DERIVATIVE AD HERBICIDE NIPPON SODA CO LTD 1998-12-22 JP disclosed